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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR1 All Species: 35.45
Human Site: T2239 Identified Species: 86.67
UniProt: Q14643 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14643 NP_001093422.1 2758 313945 T2239 K L R I Y Y T T E R D E Q G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 T2183 K C R V F N T T E R D E Q G S
Dog Lupus familis XP_851008 2757 314037 T2238 K L R I Y Y T T E R D E Q G S
Cat Felis silvestris
Mouse Mus musculus P11881 2749 313179 T2230 K L R I Y Y T T E R D E Q G S
Rat Rattus norvegicus P29994 2750 313246 T2231 K L R I Y Y T T E R D E Q G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001167530 2712 309042 T2190 K L R I Y Y T T E R D E Q G S
Frog Xenopus laevis NP_001084015 2693 306654 T2177 K L R I Y Y T T E R D E Q G S
Zebra Danio Brachydanio rerio XP_001921194 2691 306311 T2172 K L R V Y Y T T E R D E Q G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 A2324 K I K I L N T A E R D D Q G S
Honey Bee Apis mellifera XP_392236 2749 311321 T2210 K I K V L H T T E R D D Q G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 68.8 98.6 N.A. 98.2 98.2 N.A. N.A. 93.6 87.8 85.4 N.A. 58.5 62.5 N.A. N.A.
Protein Similarity: 100 N.A. 80.8 99.2 N.A. 99 98.9 N.A. N.A. 96.1 92.3 91.3 N.A. 72.1 76.7 N.A. N.A.
P-Site Identity: 100 N.A. 73.3 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 60 60 N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 80 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 20 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 100 0 0 80 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 70 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 100 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 70 0 0 20 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 80 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % S
% Thr: 0 0 0 0 0 0 100 90 0 0 0 0 0 0 0 % T
% Val: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 70 70 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _